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133 , e165654 (2023)

The best choice depends on current weight and BMI, weight-related medical conditions, blood sugar status, cardiovascular risk, liver health, kidney function, medication history, side-effect risk, muscle mass and nutrition status, cost and access, patient preference, and long-term maintenance planning

At the level of the CNS GLP-1 is produced in the hindbrain, primarily in the nucleus of the solitary tract (NTS) (Han et al., 1986

Childhood Depression Management Children and adolescents with mild to moderate depression may be best served by psychotherapy

Importantly, even moderate weight loss results in measurable improvements in blood sugar control, BP regulation and triglyceride levels (Magkos et al., 2016