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Excessive alcohol intake may reduce insulin-mediated glucose uptake and harm pancreatic islet -cells, leading to T2DM [44]

While fiber is generally healthful, excessive intake of cruciferous vegetables (broccoli, cabbage, Brussels sprouts), beans, and whole grains may increase bloating and nausea when gastric emptying is already delayed

Table I [i] PIO pioglitazone, GLP-1R glucagon-like peptide 1 receptor, SGLT2 sodium-glucose co-transporters 2, TOFO tofogliflozin, SUL sulfonylurea, MET metformin, DAPA dapagliflozin, EXE exenatide, NAFLD non-alcoholic fatty liver disease, T2D type 2 diabetes, A1C glycated hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, -GT gamma-glutamyl transferase, MRI-PDFF MRI-proton density fat fraction, MRE-LSM MR elastography-liver stiffness, RCT randomized controlled trial, EDICT Efficacy and Durability of Initial Combination Therapy, CAP controlled attenuation parameter, LSM liver stiffness measurement, BMI body mass index

20 It is important to remember that both fasting and postprandial glucose contribute to HbA1c