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To examine the specificity of AAV-CaMKIIa-Gadd45a expression in KO mPFC, we revealed that restored GADD45A signals were confined to NeuN-positive, GAD67-negative, and GFAP-negative cells, confirming selective expression in excitatory neurons without detectable ectopic expression in inhibitory neurons or glia (Fig

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Individuals randomized to continue semaglutide lost an additional 7.9% in body weight from weeks 20 to 68, whereas individuals who switched to placebo experienced a mean 6.9% increase