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Description
Berberine should be avoided during pregnancy and breastfeeding

When intestinal flora dysbiosis occurs, metabolic disorders will occur, the permeability of the intestinal tract will increase and a large amount of intestinal bacterial metabolites, bacterial components and other harmful substances will enter the liver through the portal vein via the intestinal-hepatic axis and through the enterohepatic circulation reach the liver and bind to the TLR4 of hepatocytes and exacerbate the hepatic inflammatory response, oxidative stress and lipid accumulation, which further stimulate the inflammatory response

In experimental studies, Raloxifene has been explored for its ability to support post-cycle hormone balance, maintain bone density, and mitigate estrogenic effects while preserving beneficial estrogen activity in specific tissues

These formations constitute the primary source of the majority of amyloid plaques found in mouse models of AD [35]

If patients do not tolerate a dose during dosage escalation, consider delaying dosage escalation for 4 weeks