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In reporter mice expressing yellow fluorescent protein (YFP) under a GLP-1R-Cre, expression was found in a subpopulation of enteric neurons, the action potential frequency of which could be modulated ex vivo by GLP-1 administration [23]

While happiness focuses on feeling good, and meaning is about doing good, richness is about thinking deeply and perceiving the world in a different way

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One practical consideration: during the first 2-4 weeks on GLP-1 therapy, nausea can make fasting more uncomfortable

Tirzepatide, a dual glucose-dependent insulinotropic polypeptide and GLP-1 receptor agonist, has further expanded the incretin-based treatment landscape