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The DURATION-1 and DURATION-5 clinical trials, which directly compared exenatide BID (Byetta) to exenatide QW (Bydureon), reported better HbA1c level reduction for Bydureon [119, 120]

[1] [5] This dual benefitimproved glycaemic control and weight reductionhas made them increasingly popular in clinical practice

The available data on the effects of bitter compounds in humans are limited and inconsistent

Patients should discontinue Rybelsus immediately if pancreatitis is suspected and should not resume treatment if confirmed

H., Qiu, S
