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GLP-1 agonists require caution in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

Since many individuals with Hashimoto's experience weight gain and difficulty losing weight despite adequate thyroid hormone replacement, the appetite-suppressing properties of GLP-1 agonists may appear attractive

doi: 10.1002/psc.861 35 GallwitzBWittMFlschURCreutzfeldtWSchmidtWE

Process Analytical Technology (PAT) integration in GLP-1 manufacturing is accelerating, directly tied to the QbD frameworks discussed separately in IMAPAC's manufacturing content series

Meron MK et al