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If retatrutide does not work for your specific physiology, if the side effects are not manageable, or if access becomes difficult, you can switch back to tirzepatide using the same washout principles in reverse

However, no cases of pancreatitis had occurred with these comparator treatments

Additionally, the study assessed weight and metabolic responses, finding that efinopegdutides tolerability was similar to that of semaglutide, although certain gastrointestinal side effects were more common
PMID: 26169182

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