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The GIP receptor, historically viewed with some ambiguity in the context of type 2 diabetes models, is now being re-evaluated for its role in insulin secretion, lipid metabolism, and energy homeostasis

PlexusDx's Precision Peptide Genetic Test analyzes GLP1R, GIPR, FTO, and MC4R variants to reveal predispositions in peptide-pathway response

Adverse events in relation to GLP-1R agonists for the treatment of obesity are mainly gastrointestinal side effects, including nausea, diarrhoea, vomiting and constipation, which is consistent with observations in type 2 diabetes, and rates of discontinuation due to adverse events are generally higher with GLP-1R agonists treatment compared with placebo [26, 30,31,32,33,34,35,36,37,38,39]

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