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775 nM Biological Activity Full agonist at human GLP-1, GIP, and glucagon receptors

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There are two exceptions that allow a provider to compound a GLP-1 drug: (1) if the drug is not commercially available, and (2) if the compounded drug includes a change, made for an identified individual patient, which produces for that patient a significant difference, as determined by the prescribing practitioner, between the compounded drug and the commercially available product. The identified change must be documented appropriately on the prescription or order

Andres Acosta, an obesity expert at Mayo Clinic who was not involved in the study, said that not one, but many genetic variants contribute to the differences in how people respond to these drugs