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The overall metabolic improvement may slow or halt the progressive dysfunction that characterizes untreated prediabetes

Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss

Some clinical studies also support an increased incidence of anxiety diagnosis after GLP-1 analogs, with a more pronounced impact on women (hazard ratio of 2.19 vs 1.89 in women and men, respectively) (99), although more research evaluating this question in preclinical and clinical settings is needed for a more robust conclusion

Key observed areas include: Metabolic: glucose control, energy balance, insulin secretion

Many patients with Hashimoto's disease also experience other autoimmune conditions, metabolic syndrome, or weight management challenges, which may prompt consideration of additional therapies such as GLP-1 receptor agonists