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The stool reaches the rectum but cannot exit efficiently

Functional brain imaging techniques, such as functional magnetic resonance imaging (fMRI) and fluoro-deoxy-glucose positron emission tomography (FDG-PET), have shown that the orbitofrontal cortex (OFC) is activated when individuals consume food until they feel full
Interesting emerging data: some GLP-1 users report reduced cravings for alcohol, leading to research into GLP-1 for alcohol use disorder

10.1056/NEJMoa2108269 28 GilbertM

2025;DOI: 10.1002/art.43403
