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For example, INT-777 and MN6, TGR5 selective agonists, stimulated GLP-1 secretion and improved insulin sensitivity in diet-induced obesity (DIO) mice [180, 181]

August 15, 2025: The federal court overseeing the GLP-1 receptor agonist multidistrict litigation issued a major ruling that could shape the future of lawsuits involving Ozempic and other GLP-1 medications

Through a reduction in extracellular glutamate and an increase in pro-survival signaling, Hernndez et al

Make sure that any supplement you consider has transparent third-party testing

From there, if youre still not seeing a change, it could be worth reviewing your medications with your doctorboth your GLP-1 and any others you may be taking