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Dry mouth (xerostomia) is a side effect experienced by some individuals using GLP-1 receptor agonist injections for weight loss treatment

Although tesofensine did not have a significant effect on total 24-hour energy expenditure, it increased energy expenditure during the night period when adjusted for changes in body composition

The receptors are activating, but the dose is deliberately low enough to minimize the initial adjustment period

This glucose-dependent regulation further contributes to improved glycemic control with a reduced risk of hypoglycemia

This equates to 5-9 months or more dementia-free days of life