long term use of glp 1 agonists GLP-1 Receptor as Treatments for Type 2 Diabetes The expanding role of GLP-1
Description
Obesity / chronic weight management is the fastest growing segment, driven by the escalation of world obesity and the growing body of evidence for the utility of GLP-1 therapies in weight loss

Astrup, A, Carraro, R, Finer, N, et al

This is a critical concern for anti-aging and long-term metabolic health
The short answer is YES

Among those people, about 10% are severely obese, meaning they have BMIs of 40 or greater
