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Severe symptoms-persistent vomiting, abdominal pain, or signs of pancreatitis-require immediate medical attention

Compounded semaglutide from FDA-registered 503B pharmacies following USP-797 standards can be safe, though compounded medications are not FDA-approved

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A retrospective study of insulin-treated patients with type 2 diabetes who started semaglutide found that 32.8% discontinued insulin entirely during follow-up, and 57.3% had their insulin dose reduced

[1][2] Do not increase the dose early, double up doses, combine Wegovy tablets with Wegovy injections, or use another GLP-1 medicine at the same time unless a prescriber has explicitly told you to do so