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Higher doses were associated with greater weight loss within the initial 4 weeks of treatment [see Warnings and Precautions (5.5)]

Back Harris, J (Jan 2022) 'The first insulin injection as a treatment for diabetes', Origins: Current Events in Historical Perspective

National Preferred Formulary 2026

This is because they represent indirect measures based on prescription events that are used to infer medication use and may not always reflect patients medication-taking behaviour at home

State-licensed 503A pharmacies can compound semaglutide for patient-specific prescriptions with documented clinical justification, such as an inactive-ingredient allergy or a dose not commercially available