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Since knowledge is power, especially when it comes to your health, weve broken down the science, weight-loss stats, and side effects for each of these wonder drugs

Avoid bismuth subsalicylate (Pepto-Bismol) in high doses

These shortage resolutions matter because FDA guidance on compounding indicates that compounded drugs may be appropriate when a patient's medical need cannot be met by an FDA-approved drug, or when the approved drug is not commercially available

Severe impairment hasn't been studied extensively

In the Phase 2 retatrutide trial published in the New England Journal of Medicine (2023), participants at the highest dose (12 mg) achieved a mean body weight reduction of approximately 24.2% over 48 weeks