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Patients with a history of pancreatitis require particular caution, as GLP-1 receptor agonists have been associated with rare cases of acute pancreatitis in clinical trials and post-marketing surveillance

Given the uncertainty of this initial clinical trial, additional studies exploring the effect of different GLP-1R agonists on alcohol drinking in overweight AUD patients are needed in the future

Many patients achieve excellent results with minimal or no nausea when dose escalation matches their individual tolerance

Semaglutide, the forerunner to tirzepatide (Mounjaro), is even being trialled as a treatment for Alzheimer's disease

That left, in every case, a healthy diet and exercise as the preferred solution to obesity