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UK consensus and NICE resources emphasise these mechanisms and management approaches

When there is a severe insult to the liver, the liver cells can die, and we can see this in a blood test when we look at the inflammation in the liver. In severe cases, people can die from liver failure or they need a liver transplant to save their life. That patient is unlikely to need a transplant

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Whilst these medicines offer significant therapeutic benefits, some patients report experiencing an unpleasant taste in their mouth during treatmentoften described as metallic, bitter, or simply 'off'

The approach depends on how many days have elapsed since the scheduled injection