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In STEP 1, participants without diabetes who received 2.4mg of semaglutide weekly lost an average of 14.9% of their body weight over 68 weeks

This data provides a meaningful window into what long-term tirzepatide use looks like in a clinical setting, and the safety profile remained consistent across the duration of the trial

With GLP-1 patients, its still unclear to me if it has the same impact on collagen and elastin production, but I do think it helps support skin quality in a meaningful way. Dr

Weeks 1 to 4: Starting at 2.5 mg Your first four weeks happen at 2.5 mg once weekly

What to Expect at Each Dose Level Based on clinical trial data from the SURMOUNT-1 and SURPASS-2 trials, here's what participants typically experienced at each dose level