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School of Medicine, City University of New York, Bronx, NY 10457, USA

Non-GLP-1 weight-loss meds WeightWatchers still offers a few non-GLP-1 medicines designed for weight loss, which are actually included with your membership : Metformin: This drug produces modest weight loss (a few kilograms) and is not as effective as GLP-1s for weight management [1] Combination bupropion/naltrexone: not as effective as GLP-1s but may still work for some Nutrition and exercise support This is where WeightWatchers really sets itself apart from other online weight-loss clinics

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In SURMOUNTMAINTAIN, mean (SD) age was 47 years (13.02) with a mean body weight of 114 kg (26.97), mean BMI of 40 kg/m 2 (8.07) and mean waist circumference of 119 cm (17.56) at baseline