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Conversely, those with shorter diabetes duration and better preserved beta-cell function often respond more rapidly, as their pancreatic cells retain greater capacity to respond to GLP-1 receptor stimulation

When GLP-1 receptors activate, they slow gastric emptying

However, the combination treatment did not produce greater weight loss than a very low-calorie diet alone

These trials, involving thousands of participants over extended periods, will generate the data necessary for regulatory submissions

Mechanism of action: Ozempic works by mimicking the GLP-1 hormone, which helps regulate blood sugar by increasing insulin production and slowing gastric emptying