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The good news: constipation is manageable with the right approach, and you don't have to choose between your GLP-1 medication and digestive relief

Unfortunately, backup products like Tremfya (Guselkumab) have not gained sufficient traction, leading to fatigue in the growth of the immunology business

13 Four of these have used ICP as an outcome measure, with the magnitude of treatment effect between trial arms ranging from 5.9 cmCSF (acetazolamide and diet), 41 6.0 (1.8) (by bariatric surgery) 12 and 6.2 cmCSF (through low-calorie diet)

The demand for weight loss drugs is high, and its only expected to grow

Patient disposition is shown in Figure 1
