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pylori releases toxins chronic inflammation, risk of ulcers and gastric cancer Clinical Features Acute gastritis Epigastric pain / discomfort Nausea, vomiting Anorexia Hematemesis (if severe, erosive) Chronic gastritis Often asymptomatic Dyspepsia, bloating, early satiety Iron deficiency anemia (chronic blood loss) Pernicious anemia (if autoimmune gastritis) Investigations Endoscopy: erythema, erosions, mucosal changes Biopsy: confirms H

Further studies are needed to evaluate the mechanistic connection between mtDNA polymorphisms and mitochondrial-encoded peptides in T2DM

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