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creatine and glp-1 CreatineForHealth receptor agonists (like semaglutide tirzepatide) are revolutionizing obesity and type 2 diabetes care, but up to 40% of weight loss may come from lean mass. Could help? Ribeiro I Added Creatine to My
Description
In a large Phase 3 clinical trial published in the New England Journal of Medicine, people who took the highest dose of the Wegovy pill lost an average of 16.6 percent of their body weight after 64 weeks

doi:10.1016/j.neuroscience.2011.02.023 27

Stopping the therapy often leads to rapid weight regain, undermining long-term benefits

But unlike an HSA, this one comes with a little red tape

Abbreviations AMPK: AMP-activated protein kinase DPP-4: Dipeptidyl peptidase-4 GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide 1 PPAR: Peroxisome proliferator-activated receptor References Nathan DM, Buse JB, Davidson MB et al (2009) Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes
