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Maintaining appropriate storage conditions is critical to preserving semaglutide's stability and therapeutic efficacy throughout its shelf life

8 Conclusion and future prospective The use of incretin-based therapy, particularly GLP-1 receptor agonists, has exhibited encouraging outcomes in addressing obesity and associated conditions such as diabetes mellitus type-2, cardiovascular disease, and NAFLD (non-alcoholic fatty liver disease)

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The Overlap Risk: Why Concurrent Use Is Not Recommended The Pharmaceutical Journal (Royal Pharmaceutical Society, December 2025) states that concurrent administration of tirzepatide and semaglutide "could heighten side effects" due to their "overlapping incretin activity." When both drugs are active simultaneously, the GLP-1 receptor faces amplified agonist load