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Clinically, patients on Zepbound have achieved sustained weight reductions of 15 to 20 percent over a yearconsiderably more than standard diet and exercise regimens alone offer

Additional adverse effects may include: Drowsiness Headache Insomnia Depression [21] Seizures also have potential adverse effects, so healthcare providers must monitor patients for neurological symptoms

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In one meta-analysis PIO was found to be the most effective drug for the treatment of NASH followed by Roux-en-Y gastric bypass procedure [53]
