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Repeatedly injecting into the same spot can cause local tissue changes, such as injection-site nodules or reactions, and less commonly lipohypertrophy (a localised thickening or hardening of fatty tissue), all of which can impair drug absorption and affect treatment outcomes

Home BP monitoring during dose escalation may be helpful, particularly for patients with labile BP or those on multidrug regimens

Types of rashes that can occur with semaglutide include erythema (redness), urticaria (hives), and pruritus (itchiness)

While highly effective, can semaglutide cause vomiting

The medication typically reaches peak levels 2448 hours after injection and remains detectable for 710 days with weekly dosing