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Description
Patients prescribed DOACs (apixaban, rivaroxaban, edoxaban, dabigatran) require renal function monitoring at least annually, and more frequently in those aged over 75, with low body weight, intercurrent illness, or chronic kidney disease
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Br J Pharmacol 173: 34433453, 2016

Due to the modest and unsustainable weight loss outcomes and potential carcinogenicity concerns, the FDA ultimately withdrew its approval as a weight-loss aid in 2020 (Table 2) [143,144,145]

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Lastly, although it is not necessarily a surgical complication per se , some patients do fail to lose weight (113)
