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You should not take them if any of the following apply: Medical conditions Personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) History of pancreatitis Severe kidney or liver disease Diabetic retinopathy Severe gastrointestinal disease, including gastroparesis Allergy to semaglutide or any ingredient in the tablet Pregnancy and breastfeeding Pregnant, planning pregnancy, or breastfeeding Other medications Currently taking other GLP-1 medicines (Wegovy injections, Ozempic, Rybelsus) Taking insulin or certain diabetes medications (dose adjustments may be required under medical supervision) Age Under 18 years of age If you're unsure whether Wegovy tablets are suitable for you, our prescribers can assess your circumstances through a short online consultation

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At present, the most commonly used methods are gene-modified bacteria and surface-modified bacteria, and some natural bacteria such as Lactobacillus (LAB) and Escherichia coli Nissle1917 (EcN) had been proved to be safe clinically (49, 50)