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Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement

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You cannot combine two GLP-1 medications

Blood sugar improvements may be seen within the first few weeks, but weight loss effects may take longer

Are There Studies on Combining Semaglutide and Zofran