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Description
Glucagon-like peptide 1 receptor agonist-based (GLP-1 RA) medications, including semaglutide and the dual GLP-1 RA/gastric inhibitory polypeptide (GIP) medication tirzepatide, are used to treat type 2 diabetes or obesity

Additionally, differences in patient motivation, encouragement and cooperation between assessments can impact walking distance by a similar magnitude as the effect of interventions, 70 which can produce substantial variability and be a source of performance bias in a non-blinded, uncontrolled study

doi: 10.1016/j.ejphar.2018.10.053 183 TecilazichFDinhTPradhan-NabzdykLLealETellecheaAKafanasAet al
11.4 Lean Mass Preservation Is Foundational Preserving lean mass: Protects metabolic rate Supports long-term weight maintenance Preserves functional capacity Maintains micronutrient intake indirectly Protein adequacy often has greater downstream impact than broad micronutrient supplementation

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