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Discussion The clinical management of patients with type 2 diabetes has to balance the potential benefits of controlling hyperglycemia on microvascular and macrovascular complications, [11] with possible side effects of treatment and possible harm from over intensive control of glycemia

The above studies suggest that GLP-1 can downregulate the expression of SOCS-3 and SREBP-1c in rats with nonalcoholic fatty liver disease (NAFLD), reduce hepatic TG deposition

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Many obesity specialists compare the condition to high blood pressure: Medication can help control it, but it doesn't eliminate the underlying biology
