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However, the SNAC-based approach imposed significant practical limitations that tempered its clinical impact

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MacDonald PE, Wang X, Xia F, El-kholy W, Targonsky ED, Tsushima RG, et al

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Food and Drug Administration has approved tesamorelin for the reduction of excess abdominal fat in adults with HIV-associated lipodystrophy, and that visceral-fat mechanism is part of why it appears in body-composition protocols
