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Polyphenols in yerba mate may reduce inflammation markers and support hepatic insulin sensitivity, which indirectly benefits glucose homeostasis

BCTC is also a potent antagonist of TRPV1 activated by protons 45

Funding This work and associated article processing charges were supported by Eli Lilly and Company

Consider implementing these changes gradually: Reduce intake of high-fat foods, which are digested more slowly and may exacerbate nausea and altered bowel patterns Limit caffeine and alcohol, both of which can stimulate bowel activity Avoid artificial sweeteners (particularly sorbitol and mannitol), which have laxative properties [29] Increase soluble fibre intake through oats, bananas, and cooked vegetables to help regulate stool consistency Eat smaller, more frequent meals rather than large portions Stay well-hydrated, particularly if experiencing diarrhoea, to prevent dehydration For persistent diarrhoea, oral rehydration solutions (available from pharmacies) can help maintain electrolyte balance