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GIP-induced insulin secretion and consequences for the incretin effect Endogenous GIP affects postprandial plasma glucose excursions and insulin secretion more than endogenous GLP-1, but the hormones contribute additively to postprandial glucose regulation in healthy individuals [4]

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Weight loss drug lawsuits are being filed for patients who suffered serious side effects from prescription medications

In terms of its effects, it appears to impact drinking in ways (though not necessarily mechanisms) similar to naltrexone (FDA-approved) and topiramate (prescribed off label for alcohol use disorder), which have a greater effect in reducing intensity of drinking on drinking days relative to their effects on whether someone drinks at all (i.e., abstinent days) although all of them do increase abstinent days to some degree on average)

the total population sizes in the meta-analyses ranged from 38,723 to 79,799 with median follow-up durations for the included trials ranging from 0.8 to 5.4 years