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Diarrhea Diarrhea affects about 29.7% of semaglutide 2.4 mg users in the STEP trials versus 15.9% on placebo

Conclusions In conclusion, our pilot randomised controlled trial showed that the addition of the GLP-1 agonist receptor liraglutide after LABG did not significantly improve HbA1c or weight compared to placebo at 6 months

Starting Safely With Autoimmune Disease Most providers who are comfortable prescribing GLP-1s to patients with autoimmune conditions will recommend a slower-than-standard dose escalation

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Our findings reveal that tirzepatide attenuates alcohol-induced dopamine signalling, reduces alcohol consumption, and suppresses relapse-like behaviours. Because alcohol, nicotine, and many drugs of abuse hijack the brains reward circuitry, dampening dopamine spikes could help explain why alcohol seemed less compelling to the animals