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The intraocular pressure lowering agents constitute very distinctive classes that were also regularly combined, since very early times (i.e., pilocarpine and epinephrine [31,32,33,34])

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Intramuscular injections should be given deep to minimize irritation

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Matsubara N, Naito Y, Sasaki M, Yamamoto N, Takahashi S, Uemura H

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The following strategies may help reduce discomfort whilst continuing treatment

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They should be discontinued at least two months before planned conception and are not approved for use during pregnancy

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