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A complex signaling cascade related to diabetic metabolic disorders leads to the destruction of the corneal epithelium and initiates a surface disorder with superficial punctate keratopathy, persistent erosions up to corneal ulcers

doi: 10.1183/13993003.04388-2020 86 ChalmersJDBoersmaWLonerganMJayaramLCrichtonMLKaralusNet al

There are many scenarios on this list which may be of interest to you but I am concentrating on the four which are connected to B12 deficiency

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Although HD is a genetic disease, environmental and lifestyle factors can also affect onset, progression, and severity of disease [200, 201]