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Specifically, the Nrf2 dynamics are governed by a fast increase during the first 35 h followed by a slow relaxation phase over more than 48 h

Similar findings were noted by two other prospective cohort studies which reported a dysplasia rate at index endoscopy of over 8% for patients with a new diagnosis of BE 3 cm [32, 33]

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doi: 10.3389/fphar.2025.1599816 Received 25 March 2025 Accepted 16 June 2025 Published 22 July 2025 Volume 16 - 2025 Edited by Andrs Trostchansky, Universidad de la Repblica, Uruguay Reviewed by Satish Balasaheb Nimse, Hallym University, Republic of Korea Hctor Leonardo Montecino-Garrido, Center for Processed Food Studies, Chile Updates Copyright 2025 Tauchen, Huml, Jurek, Regenstein and Ozogul

B-GOS alone raised blood acetate levels (a short-chain fatty acid), but when it was combined with olanzapine, acetate levels returned to normal, while fat tissue metabolism improved through restored GPR43 receptor expression