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Direct blockade of mTOR with sirolimus also exerts promising clinical efficacy and moderated mitochondrial oxidative stress in patients [23] and mice with SLE [24,25]

This immediate source of glutathione is considered a first line defence against oxidative stress-induced damage 12

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Examples of drugs that are in the latter class include the anti-malarial drugs dapsone and primaquine, as well as rasburicase which is normally used in the treatment tumor lysis syndrome in patients undergoing chemotherapy for hematologic cancers, but has also been used to reduce the hyperuricemia associated with gout

used a facile method of avidin-biotin chemistry to modify the red blood cell membrane with CDX peptide, which shows high bond towards nicotinic acetylcholine receptors