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64 Notably, cationic delivery strategies require careful design to support weak, reversible interactions with the cartilage matrix, because an excessively positive charge may favor tight binding, potentially limiting penetrability

2019;98:e14463

Fate of microglia during HIV-1 infection: From activation to senescence

1) but the detailed mechanisms of their development have not yet been sufficiently explained, which is one of the main reasons for the lack of effective and safe therapies
