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The most defensible summary is the narrowest one: Epitalon is a synthetic tetrapeptide with reproducible in vitro telomerase and telomere-length activity in selected human cell lines, a circumscribed rodent dataset, and an open-label Russian cohort literature suggestive of geroprotective effects in elderly populations

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Causal attribution of specific expression changes to GHK-Cu requires independent experimental validation

Post hoc analysis of another study involving 20 patients with idiopathic pulmonary fibrosis revealed higher levels of the geroprotective factor -Klotho in urine after oral D + Q administration in each of the 20 participants (86)

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