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Other miscellaneous conditions were also excluded, including excessive consumption of grapefruit, as well as possible interactions withdrug intake (antiarrhythmics, sympathomimetics, parasympatholytics, enzyme inducers, enzyme inhibitors, and antioxidants)

Nature

The permeability study demonstrated enhanced BBB (in vitro model) permeability mediated by lactoferrin receptor-targeted transcytosis, showing a 2.7-fold increase in fluorescence intensity for lactoferrin-conjugated nanoparticles compared to non-functionalized ones

The following calculation was used: FoB cell sorting for confocal microscopy and TEM was performed by MACS pre-enrichment with B cell isolation kit (Miltenyi Biotech 130-090-862)

Gclc f/f mice (hereafter described as Gclc WT) were also treated with tamoxifen to control for potential confounding effects associated with tamoxifen treatment