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It was reported that overexpression of WT DJ-1 enhances cell resistance to DA toxicity and inhibits ROS generation [136]

10.1093/cvr/cvp078 307 WangN.KoS.-H.ChaiW.LiG.BarrettE

470 In animal models of Apelin-13-caused cardiomyocyte hypertrophy and heart failure, NCOA4-activated ferritinophagy leads to the upregulation of SFXN1 expression, causing mitochondrial iron overload and mitochondrial ROS overproduction, increased lipid peroxidation, and ultimately, ferroptosis

Studies have also shown its helps maintain prostate health.* Manganese Core Minerals is a good source of manganese