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Setti, Thiago, et al

This compromises the relaxation of vascular smooth muscle cells and has a degenerative effect on the vessels causing tissue death [34] and favoring the development of microvascular complications of diabetes, such as diabetic nephropathy (DN) (Figure 4)

[209] This is the current policy on DMEPOS refills as described in the Medicare Program Integrity Manual
This leads to a gradual loss of vision, which can develop from visual disturbances such as spots and fogginess, to an almost complete loss of sight

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