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Further research is needed to determine (1) how many functionally distinct astrocyte-subsets exist, (2) which factors induce their differentiation, (3) how the underlying transcriptional programs relate to the differential secretion of astrocyte-derived mediators, and (4) whether these transcriptional subsets also correlate with different secretional and functional astrocyte subpopulations
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In addition of catalyzing the reversible transfer of acyl groups from carnitine to CoA, CRAT has an important role in the mitochondrial transport of FA for -oxidation
