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doi: 10.1016/j.canlet.2016.01.012 129 MarchenkoN

Crocetin, its glycosidic derivative (crocin), picrocrocin, and safranal are the primary bioactive ingredients of the stigma

[DOI] [PubMed] [Google Scholar] 57.Nakajima A., Aoyama Y., Nguyen T-T.L., Shin E-J., Kim H-C., Yamada S., Nakai T., Nagai T., Yokosuka A., Mimaki Y., Ohizumi Y., Yamada K

affect the function of CNS through central cholinergic and dopaminergic nerves, and the decline of learning and memory ability is often accompanied by the changes in neurotransmitter levels in related brain regions

The lyophilized powder should be stored at 2-8C in dry conditions to maintain molecular integrity and prevent degradation that could affect research results