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56 KuchinaA.BrettnerL.PaleologuL.RocoC.RosenbergA.CarignanoA.et al (2021)

10.1016/j.fct.2012.02.008 113 TangY.TianH.ShiY.GaoC.XingM.YangW.et al (2013)

[245], which can induce the release of lactate dehydrogenase (LDH) in A549 cells, inhibit the expression of GPX4, and play a role in promoting ferroptosis [246]

We propose that the seemingly opposing roles of GSH in cell survival and cell death reflect the spatial, metabolic, and microenvironmental context in which GSH homeostasis is disrupted

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